The applications from potential host countries have been received and the ‘horse trading’ has begun. The decision on the EMA issue will be made by November. There is stiff competition from competing cities and many have made significant offers in an effort to ‘land’ the agency. Here, we have compiled five of the most interesting articles of the hundreds that have been read by our expert staff on the issue. These articles look at the contenders, the issues faced by some applicants and the vagaries associated with one particular application.