Scientific Literature Services from Acorn Regulatory

Scientific literature is a significant source of information for the monitoring of the safety profile of medicinal products, particularly in relation to the detection of new safety signals or emerging safety issues. Our scientific literature services specialists can assist your company in developing a strategy and in providing you with accurate reports on your scientific literature strategy.

With global regulations constantly shifting and with the level of scientific literature progressively increasing, pharmacovigilance teams are under continued pressure to create literature strategies that are both comprehensive and flexible. Our scientific literature services specialists have developed a process to deliver a cost effective scientific literature service for client companies.

Here are some points that we consider when developing a literature review process for your company:

1. Understanding of the products and the client

The type of medicinal product (drug, medical device) should determine what type of database to use however, most well-known databases such as Medline or Embase cover most scientific and medical journals.

2. Developing a scientific literature strategy

Author abstracts are not always consistent in the choice of words relating to pharmacovigilance concepts thus, applying a search strategy helps us to eliminate background noise, giving focus to scientific publications that are most relevant to pharmacovigilance clients. It is important for us to know your products and what you are trying to achieve; the highest recall for a search would be to enter the medicinal product name and active substance name (in all their variants) only. In practice, additional text can be added to increase precision.

3. Creating a scientific literature process for your company